BDBM50030961 2-Methyl-9H-purin-6-ylamine::CHEMBL330897

SMILES: Cc1nc(N)c2[nH]cnc2n1

InChI Key: InChIKey=SMADWRYCYBUIKH-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50030961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glyceraldehyde-3-phosphate dehydrogenase liver (Homo sapiens (Human))	BDBM50030961 (2-Methyl-9H-purin-6-ylamine | CHEMBL330897) Show SMILES Cc1nc(N)c2[nH]cnc2n1 Show InChI InChI=1S/C6H7N5/c1-3-10-5(7)4-6(11-3)9-2-8-4/h2H,1H3,(H3,7,8,9,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Ghent Curated by ChEMBL					Assay Description TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana				J Med Chem 38: 3838-49 (1995) BindingDB Entry DOI: 10.7270/Q2HT2PZ4
					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver (Homo sapiens (Human))	BDBM50030961 (2-Methyl-9H-purin-6-ylamine | CHEMBL330897) Show SMILES Cc1nc(N)c2[nH]cnc2n1 Show InChI InChI=1S/C6H7N5/c1-3-10-5(7)4-6(11-3)9-2-8-4/h2H,1H3,(H3,7,8,9,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Ghent Curated by ChEMBL					Assay Description Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma brucei				J Med Chem 38: 3838-49 (1995) BindingDB Entry DOI: 10.7270/Q2HT2PZ4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50030961 (2-Methyl-9H-purin-6-ylamine | CHEMBL330897) Show SMILES Cc1nc(N)c2[nH]cnc2n1 Show InChI InChI=1S/C6H7N5/c1-3-10-5(7)4-6(11-3)9-2-8-4/h2H,1H3,(H3,7,8,9,10,11)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Charles University Curated by ChEMBL					Assay Description Inhibitory activity against purified cdc2 p34/Cyclin B obtained from M phase oocytes of the starfish Marthasterias glacialis.				J Med Chem 40: 408-12 (1997) Article DOI: 10.1021/jm960666x BindingDB Entry DOI: 10.7270/Q2GF0SNG
					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver (Homo sapiens (Human))	BDBM50030961 (2-Methyl-9H-purin-6-ylamine | CHEMBL330897) Show SMILES Cc1nc(N)c2[nH]cnc2n1 Show InChI InChI=1S/C6H7N5/c1-3-10-5(7)4-6(11-3)9-2-8-4/h2H,1H3,(H3,7,8,9,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of Ghent Curated by ChEMBL					Assay Description Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.				J Med Chem 38: 3838-49 (1995) BindingDB Entry DOI: 10.7270/Q2HT2PZ4
					More data for this Ligand-Target Pair