BDBM50031038 4-Benzyl-3-phenyl-indeno[1,2-c]pyridazin-5-one::4-benzyl-3-phenyl-5H-indeno[1,2-c]pyridazin-5-one::CHEMBL128029

SMILES: O=C1c2ccccc2-c2nnc(-c3ccccc3)c(Cc3ccccc3)c12

InChI Key: InChIKey=QBGASZYETNGMQF-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031038 (4-Benzyl-3-phenyl-indeno[1,2-c]pyridazin-5-one | 4...) Show SMILES O=C1c2ccccc2-c2nnc(-c3ccccc3)c(Cc3ccccc3)c12 Show InChI InChI=1S/C24H16N2O/c27-24-19-14-8-7-13-18(19)23-21(24)20(15-16-9-3-1-4-10-16)22(25-26-23)17-11-5-2-6-12-17/h1-14H,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase B enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50031038 (4-Benzyl-3-phenyl-indeno[1,2-c]pyridazin-5-one | 4...) Show SMILES O=C1c2ccccc2-c2nnc(-c3ccccc3)c(Cc3ccccc3)c12 Show InChI InChI=1S/C24H16N2O/c27-24-19-14-8-7-13-18(19)23-21(24)20(15-16-9-3-1-4-10-16)22(25-26-23)17-11-5-2-6-12-17/h1-14H,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of human supersomes MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031038 (4-Benzyl-3-phenyl-indeno[1,2-c]pyridazin-5-one | 4...) Show SMILES O=C1c2ccccc2-c2nnc(-c3ccccc3)c(Cc3ccccc3)c12 Show InChI InChI=1S/C24H16N2O/c27-24-19-14-8-7-13-18(19)23-21(24)20(15-16-9-3-1-4-10-16)22(25-26-23)17-11-5-2-6-12-17/h1-14H,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of rat brain MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50031038 (4-Benzyl-3-phenyl-indeno[1,2-c]pyridazin-5-one | 4...) Show SMILES O=C1c2ccccc2-c2nnc(-c3ccccc3)c(Cc3ccccc3)c12 Show InChI InChI=1S/C24H16N2O/c27-24-19-14-8-7-13-18(19)23-21(24)20(15-16-9-3-1-4-10-16)22(25-26-23)17-11-5-2-6-12-17/h1-14H,15H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase A enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair