Found 5 hits for monomerid = 50031372 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50031372
(CHEMBL3358508)Show SMILES Cc1cccc(c1)N1CCN(CCCCNC(=O)[C@@H]2CCc3ccccc3N2)CC1 |r| Show InChI InChI=1S/C25H34N4O/c1-20-7-6-9-22(19-20)29-17-15-28(16-18-29)14-5-4-13-26-25(30)24-12-11-21-8-2-3-10-23(21)27-24/h2-3,6-10,19,24,27H,4-5,11-18H2,1H3,(H,26,30)/t24-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description Binding affinity to 5HT2A receptor (unknown origin) |
J Med Chem 57: 9578-97 (2014)
Article DOI: 10.1021/jm501119j BindingDB Entry DOI: 10.7270/Q2571DM0 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50031372
(CHEMBL3358508)Show SMILES Cc1cccc(c1)N1CCN(CCCCNC(=O)[C@@H]2CCc3ccccc3N2)CC1 |r| Show InChI InChI=1S/C25H34N4O/c1-20-7-6-9-22(19-20)29-17-15-28(16-18-29)14-5-4-13-26-25(30)24-12-11-21-8-2-3-10-23(21)27-24/h2-3,6-10,19,24,27H,4-5,11-18H2,1H3,(H,26,30)/t24-/m0/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description Binding affinity to 5HT1A receptor (unknown origin) |
J Med Chem 57: 9578-97 (2014)
Article DOI: 10.1021/jm501119j BindingDB Entry DOI: 10.7270/Q2571DM0 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50031372
(CHEMBL3358508)Show SMILES Cc1cccc(c1)N1CCN(CCCCNC(=O)[C@@H]2CCc3ccccc3N2)CC1 |r| Show InChI InChI=1S/C25H34N4O/c1-20-7-6-9-22(19-20)29-17-15-28(16-18-29)14-5-4-13-26-25(30)24-12-11-21-8-2-3-10-23(21)27-24/h2-3,6-10,19,24,27H,4-5,11-18H2,1H3,(H,26,30)/t24-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description Binding affinity to 5HT2C receptor (unknown origin) |
J Med Chem 57: 9578-97 (2014)
Article DOI: 10.1021/jm501119j BindingDB Entry DOI: 10.7270/Q2571DM0 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50031372
(CHEMBL3358508)Show SMILES Cc1cccc(c1)N1CCN(CCCCNC(=O)[C@@H]2CCc3ccccc3N2)CC1 |r| Show InChI InChI=1S/C25H34N4O/c1-20-7-6-9-22(19-20)29-17-15-28(16-18-29)14-5-4-13-26-25(30)24-12-11-21-8-2-3-10-23(21)27-24/h2-3,6-10,19,24,27H,4-5,11-18H2,1H3,(H,26,30)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 159 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description Binding affinity to dopamine D3 receptor (unknown origin) |
J Med Chem 57: 9578-97 (2014)
Article DOI: 10.1021/jm501119j BindingDB Entry DOI: 10.7270/Q2571DM0 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50031372
(CHEMBL3358508)Show SMILES Cc1cccc(c1)N1CCN(CCCCNC(=O)[C@@H]2CCc3ccccc3N2)CC1 |r| Show InChI InChI=1S/C25H34N4O/c1-20-7-6-9-22(19-20)29-17-15-28(16-18-29)14-5-4-13-26-25(30)24-12-11-21-8-2-3-10-23(21)27-24/h2-3,6-10,19,24,27H,4-5,11-18H2,1H3,(H,26,30)/t24-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description Binding affinity to dopamine D2 receptor (unknown origin) |
J Med Chem 57: 9578-97 (2014)
Article DOI: 10.1021/jm501119j BindingDB Entry DOI: 10.7270/Q2571DM0 |
More data for this Ligand-Target Pair | |