BDBM50031949 3-(2-Methyl-5,6,7,8-tetrahydro-quinolin-4-yloxymethyl)-11-(1H-tetrazol-5-yl)-dibenzo[a,d]cyclohepten-5-one::CHEMBL327633

SMILES: Cc1cc(OCc2ccc3c(cc4ccccc4c(=O)c3c2)-c2nnn[nH]2)c2CCCCc2n1

InChI Key: InChIKey=UKLUCJLTIYRIDN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50031949 (3-(2-Methyl-5,6,7,8-tetrahydro-quinolin-4-yloxymet...) Show SMILES Cc1cc(OCc2ccc3c(cc4ccccc4c(=O)c3c2)-c2nnn[nH]2)c2CCCCc2n1 Show InChI InChI=1S/C27H23N5O2/c1-16-12-25(21-8-4-5-9-24(21)28-16)34-15-17-10-11-20-22(13-17)26(33)19-7-3-2-6-18(19)14-23(20)27-29-31-32-30-27/h2-3,6-7,10-14H,4-5,8-9,15H2,1H3,(H,29,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1				J Med Chem 38: 2728-41 (1995) BindingDB Entry DOI: 10.7270/Q23B5Z5Q
					More data for this Ligand-Target Pair