BDBM50032125 CHEMBL327983::N*2*-(4-Chloro-2-methyl-phenyl)-N*4*-methyl-N*4*-phenyl-quinazoline-2,4-diamine

SMILES: CN(c1ccccc1)c1nc(Nc2ccc(Cl)cc2C)nc2ccccc12

InChI Key: InChIKey=KFYFJOHDUSSJTN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50032125 (CHEMBL327983 | N*2*-(4-Chloro-2-methyl-phenyl)-N*4...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(Cl)cc2C)nc2ccccc12 Show InChI InChI=1S/C22H19ClN4/c1-15-14-16(23)12-13-19(15)24-22-25-20-11-7-6-10-18(20)21(26-22)27(2)17-8-4-3-5-9-17/h3-14H,1-2H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair