BDBM50033875 CHEMBL3358167
SMILES: CC(NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1cc(C)cc(C)c1)c1cccnc1
InChI Key:
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50033875 (CHEMBL3358167) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activity | J Med Chem 57: 9945-57 (2014) Article DOI: 10.1021/jm5011622 BindingDB Entry DOI: 10.7270/Q2FB54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50033875 (CHEMBL3358167) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activity | J Med Chem 57: 9945-57 (2014) Article DOI: 10.1021/jm5011622 BindingDB Entry DOI: 10.7270/Q2FB54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50033875 (CHEMBL3358167) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase Y181I mutant assessed as reduction in enzyme activity | J Med Chem 57: 9945-57 (2014) Article DOI: 10.1021/jm5011622 BindingDB Entry DOI: 10.7270/Q2FB54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50033875 (CHEMBL3358167) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Universit£ di Roma Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase K103N mutant assessed as reduction in enzyme activity | J Med Chem 57: 9945-57 (2014) Article DOI: 10.1021/jm5011622 BindingDB Entry DOI: 10.7270/Q2FB54K8 | |||||||||||
More data for this Ligand-Target Pair |