BDBM50034670 CHEMBL38479::Diphenyl-phosphinic acid 1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl ester

SMILES: O=C1N(COP(=O)(c2ccccc2)c2ccccc2)S(=O)(=O)c2ccccc12

InChI Key: InChIKey=QQVOJMMJOFOZMN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50034670 (CHEMBL38479 | Diphenyl-phosphinic acid 1,1,3-triox...) Show SMILES O=C1N(COP(=O)(c2ccccc2)c2ccccc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C20H16NO5PS/c22-20-18-13-7-8-14-19(18)28(24,25)21(20)15-26-27(23,16-9-3-1-4-10-16)17-11-5-2-6-12-17/h1-14H,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibitory activity against Human leukocyte elastase was determined				J Med Chem 38: 1571-4 (1995) BindingDB Entry DOI: 10.7270/Q2M32TS7
					More data for this Ligand-Target Pair