BDBM50034782 CHEMBL3360968

SMILES: COC(=O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl

InChI Key: InChIKey=ZXTOKWKHXXGVMT-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034782 (CHEMBL3360968) Show SMILES COC(=O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C22H17ClN2O4S2/c1-29-22(26)17-13-19(25(24-17)18-9-4-3-8-16(18)23)21-11-10-20(30-21)14-6-5-7-15(12-14)31(2,27)28/h3-13H,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034782 (CHEMBL3360968) Show SMILES COC(=O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C22H17ClN2O4S2/c1-29-22(26)17-13-19(25(24-17)18-9-4-3-8-16(18)23)21-11-10-20(30-21)14-6-5-7-15(12-14)31(2,27)28/h3-13H,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair