BDBM50035602 CHEMBL3356632

SMILES: CC(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1

InChI Key: InChIKey=LMUSXECLHXJHAE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50035602 (CHEMBL3356632) Show SMILES CC(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1 Show InChI InChI=1S/C19H18N2O2/c1-12(2)13-7-9-14(10-8-13)21-19(23)16-11-20-17-6-4-3-5-15(17)18(16)22/h3-12H,1-2H3,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assay				J Med Chem 57: 9776-95 (2014) Article DOI: 10.1021/jm5012808 BindingDB Entry DOI: 10.7270/Q2TH8P9K
					More data for this Ligand-Target Pair