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SMILES: O=C(NCC#C)c1cc(C(=O)c2ccccc2)n2ccccc12

InChI Key: InChIKey=XYIXAYZRODGJNH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036275   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50036275
PNG
(CHEMBL3361075)
Show SMILES O=C(NCC#C)c1cc(C(=O)c2ccccc2)n2ccccc12
Show InChI InChI=1S/C19H14N2O2/c1-2-11-20-19(23)15-13-17(21-12-7-6-10-16(15)21)18(22)14-8-4-3-5-9-14/h1,3-10,12-13H,11H2,(H,20,23)
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Article
PubMed
n/an/a 2.21E+4n/an/an/an/an/an/a



Alexandru Ioan Cuza University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant farnesyltransferase using octyl-beta-D-glucopyranoside as substrate after 15 mins by fluorescence assay

Bioorg Med Chem Lett 24: 5777-81 (2014)


Article DOI: 10.1016/j.bmcl.2014.10.044
BindingDB Entry DOI: 10.7270/Q2W95BTK
More data for this
Ligand-Target Pair