BDBM50036439 4-(5H-Dibenzo[a,d]cyclohepten-10-yl)-1-ethyl-1,2,3,6-tetrahydro-pyridine; hydrochloride::CHEMBL542029

SMILES: CCN1CCC(=CC1)C1=Cc2ccccc2Cc2ccccc12

InChI Key: InChIKey=QLEDKIKIXCMTCN-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50036439 (4-(5H-Dibenzo[a,d]cyclohepten-10-yl)-1-ethyl-1,2,3...) Show SMILES CCN1CCC(=CC1)C1=Cc2ccccc2Cc2ccccc12 |c:5,t:9| Show InChI InChI=1S/C22H23N/c1-2-23-13-11-17(12-14-23)22-16-19-8-4-3-7-18(19)15-20-9-5-6-10-21(20)22/h3-11,16H,2,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Ability to inhibit the binding of iodine-125-labelled lysergic acid diethylamide([125I]-LSD) to the S-2A serotonin receptor.				J Med Chem 38: 708-14 (1995) BindingDB Entry DOI: 10.7270/Q2PG1SCG
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50036439 (4-(5H-Dibenzo[a,d]cyclohepten-10-yl)-1-ethyl-1,2,3...) Show SMILES CCN1CCC(=CC1)C1=Cc2ccccc2Cc2ccccc12 |c:5,t:9| Show InChI InChI=1S/C22H23N/c1-2-23-13-11-17(12-14-23)22-16-19-8-4-3-7-18(19)15-20-9-5-6-10-21(20)22/h3-11,16H,2,12-15H2,1H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Ability to inhibit the binding of iodine-125-labelled lysergic acid diethylamide([125I]-LSD) to the S-2C serotonin receptor.				J Med Chem 38: 708-14 (1995) BindingDB Entry DOI: 10.7270/Q2PG1SCG
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50036439 (4-(5H-Dibenzo[a,d]cyclohepten-10-yl)-1-ethyl-1,2,3...) Show SMILES CCN1CCC(=CC1)C1=Cc2ccccc2Cc2ccccc12 |c:5,t:9| Show InChI InChI=1S/C22H23N/c1-2-23-13-11-17(12-14-23)22-16-19-8-4-3-7-18(19)15-20-9-5-6-10-21(20)22/h3-11,16H,2,12-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiperone to the Dopamine receptor D4 in COS7 cells				J Med Chem 38: 708-14 (1995) BindingDB Entry DOI: 10.7270/Q2PG1SCG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50036439 (4-(5H-Dibenzo[a,d]cyclohepten-10-yl)-1-ethyl-1,2,3...) Show SMILES CCN1CCC(=CC1)C1=Cc2ccccc2Cc2ccccc12 |c:5,t:9| Show InChI InChI=1S/C22H23N/c1-2-23-13-11-17(12-14-23)22-16-19-8-4-3-7-18(19)15-20-9-5-6-10-21(20)22/h3-11,16H,2,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Ability to inhibit the binding of [3H]spiperone to the Dopamine receptor D2L in COS7 cells				J Med Chem 38: 708-14 (1995) BindingDB Entry DOI: 10.7270/Q2PG1SCG
					More data for this Ligand-Target Pair