BDBM50036540 CHEMBL3353598

SMILES: OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)cc1)c1ncc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=WECUMEJQVKOERZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat))	BDBM50036540 (CHEMBL3353598) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)cc1)c1ncc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C20H13ClF4N2O4S/c21-17-9-14(20(23,24)25)10-26-18(17)27(11-12-1-5-15(22)6-2-12)32(30,31)16-7-3-13(4-8-16)19(28)29/h1-10H,11H2,(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
RaQualia Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPM8 assessed as inhibition of menthol induced Ca2+ influx by cell-based assay				Bioorg Med Chem Lett 24: 5364-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.074 BindingDB Entry DOI: 10.7270/Q2TB18HX
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50036540 (CHEMBL3353598) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)cc1)c1ncc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C20H13ClF4N2O4S/c21-17-9-14(20(23,24)25)10-26-18(17)27(11-12-1-5-15(22)6-2-12)32(30,31)16-7-3-13(4-8-16)19(28)29/h1-10H,11H2,(H,28,29)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
RaQualia Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influx				Bioorg Med Chem Lett 24: 5364-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.074 BindingDB Entry DOI: 10.7270/Q2TB18HX
					More data for this Ligand-Target Pair