BDBM50036711 1-(4-Fluoro-phenyl)-3-[4-(4-fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-propan-1-one::CHEMBL126437

SMILES: Fc1ccc(cc1)C(=O)CCN1CCC(=CC1)c1ccc(F)cc1

InChI Key: InChIKey=SDTHWAALASORTP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036711 (1-(4-Fluoro-phenyl)-3-[4-(4-fluoro-phenyl)-3,6-dih...) Show SMILES Fc1ccc(cc1)C(=O)CCN1CCC(=CC1)c1ccc(F)cc1 |c:15| Show InChI InChI=1S/C20H19F2NO/c21-18-5-1-15(2-6-18)16-9-12-23(13-10-16)14-11-20(24)17-3-7-19(22)8-4-17/h1-9H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
New York University Curated by ChEMBL					Assay Description Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]-haloperidol in the presence of 25 nM unlabeled spiperone				J Med Chem 36: 3923-8 (1994) BindingDB Entry DOI: 10.7270/Q2H13122
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50036711 (1-(4-Fluoro-phenyl)-3-[4-(4-fluoro-phenyl)-3,6-dih...) Show SMILES Fc1ccc(cc1)C(=O)CCN1CCC(=CC1)c1ccc(F)cc1 |c:15| Show InChI InChI=1S/C20H19F2NO/c21-18-5-1-15(2-6-18)16-9-12-23(13-10-16)14-11-20(24)17-3-7-19(22)8-4-17/h1-9H,10-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
New York University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 in bovine striatal homogenate using 200 pM [3H]- spiperone and 250 nM unlabeled ketanserin				J Med Chem 36: 3923-8 (1994) BindingDB Entry DOI: 10.7270/Q2H13122
					More data for this Ligand-Target Pair