BDBM50038876 (S)-1-[(R)-3-(2-Indan-2-yl-acetyl)-thiazolidine-4-carbonyl]-pyrrolidine-2-carbaldehyde::CHEMBL65338

SMILES: O=C[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)CC1Cc2ccccc2C1

InChI Key: InChIKey=PXBNLQKLEFHKCH-ROUUACIJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50038876 ((S)-1-[(R)-3-(2-Indan-2-yl-acetyl)-thiazolidine-4-...) Show SMILES O=C[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)CC1Cc2ccccc2C1 Show InChI InChI=1S/C20H24N2O3S/c23-11-17-6-3-7-21(17)20(25)18-12-26-13-22(18)19(24)10-14-8-15-4-1-2-5-16(15)9-14/h1-2,4-5,11,14,17-18H,3,6-10,12-13H2/t17-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Zeria Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.				J Med Chem 37: 2071-8 (1994) BindingDB Entry DOI: 10.7270/Q270822J
					More data for this Ligand-Target Pair