BDBM50040017 4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid::CHEMBL100623
SMILES: CCc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
InChI Key: InChIKey=RJKMEUBHGGZRDO-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-9-cis-RA binding to baculovirus expressed retinoid receptor RXR alpha | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human)) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Effective concentration against retinoid receptor isoform (RAR alpha) expressed in CV-1 cells | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid X receptor gamma (Mus musculus) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-9-cis-RA binding to baculovirus expressed retinoid receptor RXR gamma | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid X receptor beta (Mus musculus) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-9-cis-RA binding to baculovirus expressed retinoid receptor RXR beta | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid receptor (Homo sapiens (Human)) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Effective concentration against retinoid receptor isoform (RAR beta) expressed in CV-1 cells | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid receptor (Homo sapiens (Human)) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-ATRA binding to baculovirus expressed retinoid receptor RAR beta | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid X receptor beta (Mus musculus) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 145 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Effective concentration against retinoid receptor isoform (RXR beta) expressed in CV-1 cells | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human)) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-ATRA binding to baculovirus expressed retinoid receptor RAR alpha | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid receptor (Homo sapiens (Human)) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Tested for binding affinity against [3H]-ATRA binding to retinoid receptor isoform (RAR gamma) expressed in baculovirus | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 115 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Effective concentration against retinoid receptor isoform (RXR alpha) expressed in CV-1 cells | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid X receptor gamma (Mus musculus) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 136 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Effective concentration against retinoid receptor isoform (RXR gamma) expressed in CV-1 cells | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid receptor (Homo sapiens (Human)) | BDBM50040017 (4-[1-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Effective concentration against retinoid receptor isoform (RAR gamma) expressed in CV-1 cells | J Med Chem 37: 2930-41 (1994) BindingDB Entry DOI: 10.7270/Q27080G3 | |||||||||||
More data for this Ligand-Target Pair |