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SMILES: CN1CCN(CC1)C1=Nc2ccccc2N(C=O)c2ncccc12

InChI Key: InChIKey=IAWYTCDIHYGEQM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50040240 (5-(4-Methyl-piperazin-1-yl)-benzo[b]pyrido[2,3-e][...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2N(C=O)c2ncccc12 |t:8| Show InChI InChI=1S/C18H19N5O/c1-21-9-11-22(12-10-21)18-14-5-4-8-19-17(14)23(13-24)16-7-3-2-6-15(16)20-18/h2-8,13H,9-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity against Muscarinic acetylcholine receptors in rat brain.				J Med Chem 36: 2107-14 (1993) BindingDB Entry DOI: 10.7270/Q22B8X37
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50040240 (5-(4-Methyl-piperazin-1-yl)-benzo[b]pyrido[2,3-e][...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2N(C=O)c2ncccc12 |t:8| Show InChI InChI=1S/C18H19N5O/c1-21-9-11-22(12-10-21)18-14-5-4-8-19-17(14)23(13-24)16-7-3-2-6-15(16)20-18/h2-8,13H,9-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity against rat 5-hydroxytryptamine 2 receptor.				J Med Chem 36: 2107-14 (1993) BindingDB Entry DOI: 10.7270/Q22B8X37
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50040240 (5-(4-Methyl-piperazin-1-yl)-benzo[b]pyrido[2,3-e][...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2N(C=O)c2ncccc12 |t:8| Show InChI InChI=1S/C18H19N5O/c1-21-9-11-22(12-10-21)18-14-5-4-8-19-17(14)23(13-24)16-7-3-2-6-15(16)20-18/h2-8,13H,9-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity against Dopamine receptor D1 in rat striatal tissue				J Med Chem 36: 2107-14 (1993) BindingDB Entry DOI: 10.7270/Q22B8X37
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50040240 (5-(4-Methyl-piperazin-1-yl)-benzo[b]pyrido[2,3-e][...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2N(C=O)c2ncccc12 |t:8| Show InChI InChI=1S/C18H19N5O/c1-21-9-11-22(12-10-21)18-14-5-4-8-19-17(14)23(13-24)16-7-3-2-6-15(16)20-18/h2-8,13H,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description In vitro binding affinity against Dopamine D2 receptor in rat striatal tissue.				J Med Chem 36: 2107-14 (1993) BindingDB Entry DOI: 10.7270/Q22B8X37
					More data for this Ligand-Target Pair