BDBM50040672 1-(1-Methyl-2-oxo-5-piperidin-1-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-m-tolyl-urea::CHEMBL350853

SMILES: CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)N1CCCCC1

InChI Key: InChIKey=BDZOCUCJHUMDAN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50040672 (1-(1-Methyl-2-oxo-5-piperidin-1-yl-2,3-dihydro-1H-...) Show SMILES CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)N1CCCCC1 |c:9| Show InChI InChI=1S/C23H27N5O2/c1-16-9-8-10-17(15-16)24-23(30)26-20-22(29)27(2)19-12-5-4-11-18(19)21(25-20)28-13-6-3-7-14-28/h4-5,8-12,15,20H,3,6-7,13-14H2,1-2H3,(H2,24,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding activity against Cholecystokinin type A receptor from rat pancreas using [125]BH CCK-8s as radioligand.				J Med Chem 37: 719-21 (1994) BindingDB Entry DOI: 10.7270/Q2QN67FP
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50040672 (1-(1-Methyl-2-oxo-5-piperidin-1-yl-2,3-dihydro-1H-...) Show SMILES CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)N1CCCCC1 |c:9| Show InChI InChI=1S/C23H27N5O2/c1-16-9-8-10-17(15-16)24-23(30)26-20-22(29)27(2)19-12-5-4-11-18(19)21(25-20)28-13-6-3-7-14-28/h4-5,8-12,15,20H,3,6-7,13-14H2,1-2H3,(H2,24,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding activity against Cholecystokinin type B receptor from guinea pig cortex using [125]BH CCK-8s as radioligand.				J Med Chem 37: 719-21 (1994) BindingDB Entry DOI: 10.7270/Q2QN67FP
					More data for this Ligand-Target Pair