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SMILES: CC(C)c1cccc(C(C)C)c1NC(=O)C1c2ccccc2CCc2ccccc12

InChI Key: InChIKey=MXOWQWXCYWMGMV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040826   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50040826
PNG
(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-carbox...)
Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)C1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C28H31NO/c1-18(2)22-14-9-15-23(19(3)4)27(22)29-28(30)26-24-12-7-5-10-20(24)16-17-21-11-6-8-13-25(21)26/h5-15,18-19,26H,16-17H2,1-4H3,(H,29,30)
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n/an/a 40n/an/an/an/an/an/a



Kyowa Hakko Kogyo Company

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbits

J Med Chem 37: 804-10 (1994)


BindingDB Entry DOI: 10.7270/Q20C4TTM
More data for this
Ligand-Target Pair