BDBM50041315 5-Hydroxy-2-pyridin-4-ylmethyl-indan-1-one::CHEMBL24279

SMILES: Oc1ccc2C(=O)C(Cc3ccncc3)Cc2c1

InChI Key: InChIKey=QBNIMNDGESXBEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50041315 (5-Hydroxy-2-pyridin-4-ylmethyl-indan-1-one | CHEMB...) Show SMILES Oc1ccc2C(=O)C(Cc3ccncc3)Cc2c1 Show InChI InChI=1S/C15H13NO2/c17-13-1-2-14-11(9-13)8-12(15(14)18)7-10-3-5-16-6-4-10/h1-6,9,12,17H,7-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Inhibition of human Placental Cytochrome P450 19A1 in vitro using human placental microsomes and testosterone				J Med Chem 37: 1275-81 (1994) BindingDB Entry DOI: 10.7270/Q2XD10QX
					More data for this Ligand-Target Pair