BDBM50041473 3-Iodo-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-N-pyridin-2-yl-benzamide::CHEMBL416398

SMILES: COc1ccccc1N1CCN(CCN(C(=O)c2cccc(I)c2)c2ccccn2)CC1

InChI Key: InChIKey=NZJKKAUVFSXIBG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50041473 (3-Iodo-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)c2cccc(I)c2)c2ccccn2)CC1 Show InChI InChI=1S/C25H27IN4O2/c1-32-23-10-3-2-9-22(23)29-16-13-28(14-17-29)15-18-30(24-11-4-5-12-27-24)25(31)20-7-6-8-21(26)19-20/h2-12,19H,13-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of binding of [125I]8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenates				J Med Chem 37: 1406-7 (1994) BindingDB Entry DOI: 10.7270/Q29Z95JQ
					More data for this Ligand-Target Pair