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BDBM50042554 5-Butyl-2-ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-pyrazole-3-carboxylic acid::CHEMBL431887

SMILES: CCCCc1nn(CC)c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=UXNPBCUEDIVJJE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50042554   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin II type 1a (AT-1a) receptor


(RABBIT)		BDBM50042554
PNG
(5-Butyl-2-ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-...)
Show SMILES CCCCc1nn(CC)c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H26N6O2/c1-3-5-10-21-20(22(24(31)32)30(4-2)27-21)15-16-11-13-17(14-12-16)18-8-6-7-9-19(18)23-25-28-29-26-23/h6-9,11-14H,3-5,10,15H2,1-2H3,(H,31,32)(H,25,26,28,29)
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KEGG

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PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 2.70n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1

J Med Chem 36: 3595-605 (1994)


BindingDB Entry DOI: 10.7270/Q25Q4V5H
More data for this
Ligand-Target Pair