BDBM50042742 CHEMBL340367::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-(3-phenoxy-phenyl)-acetic acid

SMILES: CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1cccc(Oc2ccccc2)c1

InChI Key: InChIKey=CPGLLVIAWAHLKY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50042742 (CHEMBL340367 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C37H41N3O4/c1-6-13-27-20-26(23-40-32(8-3)39-33-24(4)19-25(5)38-36(33)40)21-28(14-7-2)34(27)44-35(37(41)42)29-15-12-18-31(22-29)43-30-16-10-9-11-17-30/h9-12,15-22,35H,6-8,13-14,23H2,1-5H3,(H,41,42)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [1251][Sar1,IIe8]AII from rat midbrain angiotensin II (AT2) receptor				J Med Chem 36: 3738-42 (1994) BindingDB Entry DOI: 10.7270/Q2J1027W
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50042742 (CHEMBL340367 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C37H41N3O4/c1-6-13-27-20-26(23-40-32(8-3)39-33-24(4)19-25(5)38-36(33)40)21-28(14-7-2)34(27)44-35(37(41)42)29-15-12-18-31(22-29)43-30-16-10-9-11-17-30/h9-12,15-22,35H,6-8,13-14,23H2,1-5H3,(H,41,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [1251][Sar1,IIe8]AII from rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3738-42 (1994) BindingDB Entry DOI: 10.7270/Q2J1027W
					More data for this Ligand-Target Pair