BindingDB logo
myBDB logout

null

SMILES: CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CC(C)C)[C@@H](S)CC(=O)OC

InChI Key: InChIKey=BFLGZTXJYJUDGJ-SQNIBIBYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043228   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interstitial collagenase


(Homo sapiens (Human))		BDBM50043228
PNG
(3-Mercapto-4-[2-(4-methoxy-phenyl)-1-methylcarbamo...)
Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CC(C)C)[C@@H](S)CC(=O)OC
Show InChI InChI=1S/C21H32N2O5S/c1-13(2)10-16(18(29)12-19(24)28-5)20(25)23-17(21(26)22-3)11-14-6-8-15(27-4)9-7-14/h6-9,13,16-18,29H,10-12H2,1-5H3,(H,22,26)(H,23,25)/t16-,17+,18+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.10n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.

J Med Chem 36: 4030-9 (1994)


BindingDB Entry DOI: 10.7270/Q2028QM3
More data for this
Ligand-Target Pair