Found 9 hits for monomerid = 50043287 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit&aagrove; degli Studi di Milano
Curated by PDSP Ki Database
| |
Br J Pharmacol 124: 485-92 (1998)
Article DOI: 10.1038/sj.bjp.0701860 BindingDB Entry DOI: 10.7270/Q29885KW |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.0360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino
Curated by ChEMBL
| Assay Description Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin (100 pM) as labelled ligand |
J Med Chem 40: 2003-10 (1997)
Article DOI: 10.1021/jm960653j BindingDB Entry DOI: 10.7270/Q2CR5X2K |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.0360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino
Curated by ChEMBL
| Assay Description Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligand |
J Med Chem 40: 1990-2002 (1997)
Article DOI: 10.1021/jm960651z BindingDB Entry DOI: 10.7270/Q2HD7ZCK |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.0580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Urbino
Curated by ChEMBL
| Assay Description Inhibition of 2-[125I]iodomelatonin binding to melatonin receptor in quail brain as 1/Ka |
J Med Chem 36: 4069-74 (1993)
Article DOI: 10.1021/jm00077a010 BindingDB Entry DOI: 10.7270/Q2KP84VP |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit&agrove; degli Studi di Milano
Curated by PDSP Ki Database
| |
Br J Pharmacol 127: 1288-94 (1999)
Article DOI: 10.1038/sj.bjp.0702658 BindingDB Entry DOI: 10.7270/Q20G3HQ6 |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King's College
Curated by PDSP Ki Database
| |
Biol Cell 89: 531-7 (1997)
Article DOI: 10.1016/s0248-4900(98)80009-9 BindingDB Entry DOI: 10.7270/Q2JS9P06 |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King's College
Curated by PDSP Ki Database
| |
Biol Cell 89: 531-7 (1997)
Article DOI: 10.1016/s0248-4900(98)80009-9 BindingDB Entry DOI: 10.7270/Q2JS9P06 |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino
Curated by ChEMBL
| Assay Description Inhibitory activity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligand |
J Med Chem 40: 2003-10 (1997)
Article DOI: 10.1021/jm960653j BindingDB Entry DOI: 10.7270/Q2CR5X2K |
More data for this Ligand-Target Pair | |
Melatonin receptor
(Homo sapiens (Human)) | BDBM50043287
(CHEMBL33415 | Melatonin,2-Bromo | N-[2-(2-Bromo-5-...)Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino
Curated by ChEMBL
| Assay Description Inhibitory activity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as radiolabeled ligand |
J Med Chem 40: 1990-2002 (1997)
Article DOI: 10.1021/jm960651z BindingDB Entry DOI: 10.7270/Q2HD7ZCK |
More data for this Ligand-Target Pair | |