BDBM50043356 1,8-Dihydroxy-10-[2-(4-nitro-phenyl)-acetyl]-10H-anthracen-9-one::CHEMBL134069

SMILES: Oc1cccc2C(C(=O)Cc3ccc(cc3)[N+]([O-])=O)c3cccc(O)c3C(=O)c12

InChI Key: InChIKey=FTMIEKKGADRIGC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043356 (1,8-Dihydroxy-10-[2-(4-nitro-phenyl)-acetyl]-10H-a...) Show SMILES Oc1cccc2C(C(=O)Cc3ccc(cc3)[N+]([O-])=O)c3cccc(O)c3C(=O)c12 Show InChI InChI=1S/C22H15NO6/c24-16-5-1-3-14-19(15-4-2-6-17(25)21(15)22(27)20(14)16)18(26)11-12-7-9-13(10-8-12)23(28)29/h1-10,19,24-25H,11H2	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomes				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043356 (1,8-Dihydroxy-10-[2-(4-nitro-phenyl)-acetyl]-10H-a...) Show SMILES Oc1cccc2C(C(=O)Cc3ccc(cc3)[N+]([O-])=O)c3cccc(O)c3C(=O)c12 Show InChI InChI=1S/C22H15NO6/c24-16-5-1-3-14-19(15-4-2-6-17(25)21(15)22(27)20(14)16)18(26)11-12-7-9-13(10-8-12)23(28)29/h1-10,19,24-25H,11H2	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair