BDBM50043465 CHEMBL334832::{Allyl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-methyl-phenyl]-amino}-o-tolyl-acetic acid

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC=C)C(C(O)=O)c2ccccc2C)c(C)c1

InChI Key: InChIKey=SWCATIMZEVVQBX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (RAT)	BDBM50043465 (CHEMBL334832 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC=C)C(C(O)=O)c2ccccc2C)c(C)c1 Show InChI InChI=1S/C30H34N4O2/c1-7-15-33(28(30(35)36)24-12-10-9-11-19(24)3)25-14-13-23(17-20(25)4)18-34-26(8-2)32-27-21(5)16-22(6)31-29(27)34/h7,9-14,16-17,28H,1,8,15,18H2,2-6H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043465 (CHEMBL334832 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC=C)C(C(O)=O)c2ccccc2C)c(C)c1 Show InChI InChI=1S/C30H34N4O2/c1-7-15-33(28(30(35)36)24-12-10-9-11-19(24)3)25-14-13-23(17-20(25)4)18-34-26(8-2)32-27-21(5)16-22(6)31-29(27)34/h7,9-14,16-17,28H,1,8,15,18H2,2-6H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair