BDBM50043889 1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL8507

SMILES: COc1ccc2C(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)=CCCc2c1

InChI Key: InChIKey=RTTLUSMWCVHYGQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50043889 (1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...) Show SMILES COc1ccc2C(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)=CCCc2c1 |c:27| Show InChI InChI=1S/C25H29F3N2O/c1-31-23-10-11-24-19(5-2-6-20(24)17-23)7-4-12-29-13-15-30(16-14-29)22-9-3-8-21(18-22)25(26,27)28/h3,5,8-11,17-18H,2,4,6-7,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description Inhibition of binding of radioligand [3H]-spiroperidol to dopamine D2 receptor in rat striatal membranes				J Med Chem 37: 99-104 (1994) BindingDB Entry DOI: 10.7270/Q2NP23GP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50043889 (1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propy...) Show SMILES COc1ccc2C(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)=CCCc2c1 |c:27| Show InChI InChI=1S/C25H29F3N2O/c1-31-23-10-11-24-19(5-2-6-20(24)17-23)7-4-12-29-13-15-30(16-14-29)22-9-3-8-21(18-22)25(26,27)28/h3,5,8-11,17-18H,2,4,6-7,12-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit binding of radioligand [3H]-8-OH-DPAT to 5-hydroxytryptamine 1A receptor in rat cerebral cortex				J Med Chem 37: 99-104 (1994) BindingDB Entry DOI: 10.7270/Q2NP23GP
					More data for this Ligand-Target Pair