BDBM50044229 CHEMBL3218919

SMILES: Cc1ccsc1C(=O)Nc1nc2c(C)cc(C)cc2s1

InChI Key: InChIKey=GSHQRYRMPNCEPF-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50044229 (CHEMBL3218919) Show SMILES Cc1ccsc1C(=O)Nc1nc2c(C)cc(C)cc2s1 Show InChI InChI=1S/C15H14N2OS2/c1-8-6-10(3)12-11(7-8)20-15(16-12)17-14(18)13-9(2)4-5-19-13/h4-7H,1-3H3,(H,16,17,18)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description In vivo inhibition of leutenising hormone in rats.				J Med Chem 61: 5794-5804 (2018) Article DOI: 10.1021/acs.jmedchem.7b01314 BindingDB Entry DOI: 10.7270/Q2M32Z85
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50044229 (CHEMBL3218919) Show SMILES Cc1ccsc1C(=O)Nc1nc2c(C)cc(C)cc2s1 Show InChI InChI=1S/C15H14N2OS2/c1-8-6-10(3)12-11(7-8)20-15(16-12)17-14(18)13-9(2)4-5-19-13/h4-7H,1-3H3,(H,16,17,18)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Agonist activity at human RoRc-LBD expressed in Jurkat cells assessed as IL-17 reporter activity by luciferase assay in absence of anti-CD3				J Med Chem 57: 5871-92 (2014) Article DOI: 10.1021/jm401901d BindingDB Entry DOI: 10.7270/Q2M0473Z
					More data for this Ligand-Target Pair