BDBM50046153 CHEMBL3310851

SMILES: CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=SIHGQXZVZBAKAC-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50046153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50046153 (CHEMBL3310851) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H14F3N3O3S/c1-10(22)19-12-6-8-14(9-7-12)25(23,24)21-20-13-4-2-11(3-5-13)15(16,17)18/h2-9,20-21H,1H3,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO expressed in Escherichia coli using N-formylkynurenine as substrate incubated for 1 hr prior to NaOH addition mea...				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50046153 (CHEMBL3310851) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H14F3N3O3S/c1-10(22)19-12-6-8-14(9-7-12)25(23,24)21-20-13-4-2-11(3-5-13)15(16,17)18/h2-9,20-21H,1H3,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	181	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair