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SMILES: COc1ccc(OC)c(c1)C1C2=C(COC2=O)Nc2c1c1cccnc1c1ncccc21

InChI Key: InChIKey=ZREUNNDAALIMRM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046751   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)		BDBM50046751
PNG
(CHEMBL3309646)
Show SMILES COc1ccc(OC)c(c1)C1C2=C(COC2=O)Nc2c1c1cccnc1c1ncccc21 |t:12|
Show InChI InChI=1S/C25H19N3O4/c1-30-13-7-8-18(31-2)16(11-13)19-20-14-5-3-9-26-23(14)24-15(6-4-10-27-24)22(20)28-17-12-32-25(29)21(17)19/h3-11,19,28H,12H2,1-2H3
UniProtKB/TrEMBL

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Similars
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of bovine brain tubulin polymerization measured for 1 hr at 1 min intervals by fluorescence assay

Bioorg Med Chem Lett 24: 3356-60 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.096
BindingDB Entry DOI: 10.7270/Q2X068PJ
More data for this
Ligand-Target Pair