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BDBM50047299 3-{2-[3-(4-Hept-6-ynylcarbamoyl-oxazol-2-yl)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl]-phenyl}-propionic acid::CHEMBL416943

SMILES: OC(=O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(co1)C(=O)NCCCCCC#C

InChI Key: InChIKey=ZLSQZUKYIFZOES-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047299   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))		BDBM50047299
PNG
(3-{2-[3-(4-Hept-6-ynylcarbamoyl-oxazol-2-yl)-7-oxa...)
Show SMILES OC(=O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(co1)C(=O)NCCCCCC#C |THB:19:18:17:15.14,11:12:17:15.14|
Show InChI InChI=1S/C27H32N2O5/c1-2-3-4-5-8-15-28-26(32)21-17-33-27(29-21)25-20(22-12-13-23(25)34-22)16-19-10-7-6-9-18(19)11-14-24(30)31/h1,6-7,9-10,17,20,22-23,25H,3-5,8,11-16H2,(H,28,32)(H,30,31)
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PC sid
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Similars
PubMed
n/an/an/a 4.70n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligand

J Med Chem 36: 1401-17 (1993)


BindingDB Entry DOI: 10.7270/Q2TX3DF9
More data for this
Ligand-Target Pair