BDBM50047504 1-{2-Dimethylamino-6-[4-(4-phenyl-imidazol-1-yl)-butoxy]-phenyl}-3-pentyl-urea::CHEMBL44358

SMILES: CCCCCNC(=O)Nc1c(OCCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C

InChI Key: InChIKey=BEZRXKMOKQLKQE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047504 (1-{2-Dimethylamino-6-[4-(4-phenyl-imidazol-1-yl)-b...) Show SMILES CCCCCNC(=O)Nc1c(OCCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O2/c1-4-5-9-17-28-27(33)30-26-24(31(2)3)15-12-16-25(26)34-19-11-10-18-32-20-23(29-21-32)22-13-7-6-8-14-22/h6-8,12-16,20-21H,4-5,9-11,17-19H2,1-3H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047504 (1-{2-Dimethylamino-6-[4-(4-phenyl-imidazol-1-yl)-b...) Show SMILES CCCCCNC(=O)Nc1c(OCCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O2/c1-4-5-9-17-28-27(33)30-26-24(31(2)3)15-12-16-25(26)34-19-11-10-18-32-20-23(29-21-32)22-13-7-6-8-14-22/h6-8,12-16,20-21H,4-5,9-11,17-19H2,1-3H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair