BDBM50047505 1-{2-Dimethylamino-6-[4-(5-methyl-4-phenyl-imidazol-1-yl)-butyl]-phenyl}-3-pentyl-urea::CHEMBL43095

SMILES: CCCCCNC(=O)Nc1c(CCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C

InChI Key: InChIKey=FLASAYJQWIWHOK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047505 (1-{2-Dimethylamino-6-[4-(5-methyl-4-phenyl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(CCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C28H39N5O/c1-5-6-11-19-29-28(34)31-27-24(17-13-18-25(27)32(3)4)16-10-12-20-33-21-30-26(22(33)2)23-14-8-7-9-15-23/h7-9,13-15,17-18,21H,5-6,10-12,16,19-20H2,1-4H3,(H2,29,31,34)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047505 (1-{2-Dimethylamino-6-[4-(5-methyl-4-phenyl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(CCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C28H39N5O/c1-5-6-11-19-29-28(34)31-27-24(17-13-18-25(27)32(3)4)16-10-12-20-33-21-30-26(22(33)2)23-14-8-7-9-15-23/h7-9,13-15,17-18,21H,5-6,10-12,16,19-20H2,1-4H3,(H2,29,31,34)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair