BDBM50048276 4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-propenyl]-benzoic acid::CHEMBL421773

SMILES: C\C(=C/c1ccc(cc1)C(O)=O)c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=FMXQRDBLCLYHLF-LZYBPNLTSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoid receptor (Homo sapiens (Human))	BDBM50048276 (4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-prope...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2 |TLB:26:25:28:20.21.22,26:21:28:27.25.24,THB:24:25:20:28.23.22,24:23:20:27.25.26| Show InChI InChI=1S/C26H28O3/c1-16(8-17-2-4-21(5-3-17)25(28)29)22-6-7-24(27)23(12-22)26-13-18-9-19(14-26)11-20(10-18)15-26/h2-8,12,18-20,27H,9-11,13-15H2,1H3,(H,28,29)/b16-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIRD GALDERMA Curated by ChEMBL					Assay Description Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand				J Med Chem 38: 4993-5006 (1996) BindingDB Entry DOI: 10.7270/Q20G3J8S
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50048276 (4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-prope...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2 |TLB:26:25:28:20.21.22,26:21:28:27.25.24,THB:24:25:20:28.23.22,24:23:20:27.25.26| Show InChI InChI=1S/C26H28O3/c1-16(8-17-2-4-21(5-3-17)25(28)29)22-6-7-24(27)23(12-22)26-13-18-9-19(14-26)11-20(10-18)15-26/h2-8,12,18-20,27H,9-11,13-15H2,1H3,(H,28,29)/b16-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIRD GALDERMA Curated by ChEMBL					Assay Description Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand				J Med Chem 38: 4993-5006 (1996) BindingDB Entry DOI: 10.7270/Q20G3J8S
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50048276 (4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-prope...) Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2 |TLB:26:25:28:20.21.22,26:21:28:27.25.24,THB:24:25:20:28.23.22,24:23:20:27.25.26| Show InChI InChI=1S/C26H28O3/c1-16(8-17-2-4-21(5-3-17)25(28)29)22-6-7-24(27)23(12-22)26-13-18-9-19(14-26)11-20(10-18)15-26/h2-8,12,18-20,27H,9-11,13-15H2,1H3,(H,28,29)/b16-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIRD GALDERMA Curated by ChEMBL					Assay Description Binding affinity to retinoic acid receptor beta using [3H]-CD 367 as radioligand				J Med Chem 38: 4993-5006 (1996) BindingDB Entry DOI: 10.7270/Q20G3J8S
					More data for this Ligand-Target Pair