BDBM50048575 (5-Methoxy-indol-1-yl)-propyl-pyridin-4-yl-amine::CHEMBL155211

SMILES: CCCN(c1ccncc1)n1ccc2cc(OC)ccc12

InChI Key: InChIKey=SYFFAEMYTWTOCA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50048575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50048575 ((5-Methoxy-indol-1-yl)-propyl-pyridin-4-yl-amine |...) Show SMILES CCCN(c1ccncc1)n1ccc2cc(OC)ccc12 Show InChI InChI=1S/C17H19N3O/c1-3-11-19(15-6-9-18-10-7-15)20-12-8-14-13-16(21-2)4-5-17(14)20/h4-10,12-13H,3,11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against norepinephrine (NE) uptake in rat whole brain synaptosome preparation				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50048575 ((5-Methoxy-indol-1-yl)-propyl-pyridin-4-yl-amine |...) Show SMILES CCCN(c1ccncc1)n1ccc2cc(OC)ccc12 Show InChI InChI=1S/C17H19N3O/c1-3-11-19(15-6-9-18-10-7-15)20-12-8-14-13-16(21-2)4-5-17(14)20/h4-10,12-13H,3,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the presence of Zn				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50048575 ((5-Methoxy-indol-1-yl)-propyl-pyridin-4-yl-amine |...) Show SMILES CCCN(c1ccncc1)n1ccc2cc(OC)ccc12 Show InChI InChI=1S/C17H19N3O/c1-3-11-19(15-6-9-18-10-7-15)20-12-8-14-13-16(21-2)4-5-17(14)20/h4-10,12-13H,3,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the absence of Zn				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50048575 ((5-Methoxy-indol-1-yl)-propyl-pyridin-4-yl-amine |...) Show SMILES CCCN(c1ccncc1)n1ccc2cc(OC)ccc12 Show InChI InChI=1S/C17H19N3O/c1-3-11-19(15-6-9-18-10-7-15)20-12-8-14-13-16(21-2)4-5-17(14)20/h4-10,12-13H,3,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against acetylcholinesterase in rat striatal preparation				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair