BDBM50049119 1-(2'-Carboxy-biphenyl-4-ylmethyl)-2-propyl-1H-imidazole-4,5-dicarboxylic acid::CHEMBL300186

SMILES: CCCc1nc(C(O)=O)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=HFTHXQBUJNFWTN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50049119 (1-(2'-Carboxy-biphenyl-4-ylmethyl)-2-propyl-1H-imi...) Show SMILES CCCc1nc(C(O)=O)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H20N2O6/c1-2-5-17-23-18(21(27)28)19(22(29)30)24(17)12-13-8-10-14(11-9-13)15-6-3-4-7-16(15)20(25)26/h3-4,6-11H,2,5,12H2,1H3,(H,25,26)(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [125l]-All binding to bovine adrenal cortex				Bioorg Med Chem Lett 4: 177-182 (1994) Article DOI: 10.1016/S0960-894X(01)81143-4 BindingDB Entry DOI: 10.7270/Q2BG2NZQ
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50049119 (1-(2'-Carboxy-biphenyl-4-ylmethyl)-2-propyl-1H-imi...) Show SMILES CCCc1nc(C(O)=O)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C22H20N2O6/c1-2-5-17-23-18(21(27)28)19(22(29)30)24(17)12-13-8-10-14(11-9-13)15-6-3-4-7-16(15)20(25)26/h3-4,6-11H,2,5,12H2,1H3,(H,25,26)(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair