null
SMILES: CC(C)(N)CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C1=O
InChI Key: InChIKey=SBJLJOFPWOYATP-XMMPIXPASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50049481 ((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding Affinity of the compound against Growth hormone secretagogue receptor of swine using [35S]-MK-0677 as radioligand | J Med Chem 39: 1767-70 (1996) Article DOI: 10.1021/jm960054c BindingDB Entry DOI: 10.7270/Q2BK1BDG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ghrelin receptor () | BDBM50049481 ((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...) | Reactome pathway KEGG GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S Curated by ChEMBL | Assay Description Inhibition of the compound against rat growth hormone secretagogue (GHS) receptor | J Med Chem 47: 888-99 (2004) Article DOI: 10.1021/jm0309452 BindingDB Entry DOI: 10.7270/Q2SN08D0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone-releasing hormone receptor (Rattus norvegicus) | BDBM50049481 ((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Ability to release growth hormone in a rat pituitary cell assay | Bioorg Med Chem Lett 7: 2319-2324 (1997) Article DOI: 10.1016/S0960-894X(97)00421-6 BindingDB Entry DOI: 10.7270/Q23R0V2C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Homo sapiens (Human)) | BDBM50049481 ((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S Curated by ChEMBL | Assay Description Inhibition of the compound against human angiotensin II receptor, type 1 (AG2-R) | J Med Chem 47: 888-99 (2004) Article DOI: 10.1021/jm0309452 BindingDB Entry DOI: 10.7270/Q2SN08D0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50049481 ((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S Curated by ChEMBL | Assay Description Inhibition of the compound against human growth hormone secretagogue (GHS) receptor | J Med Chem 47: 888-99 (2004) Article DOI: 10.1021/jm0309452 BindingDB Entry DOI: 10.7270/Q2SN08D0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ghrelin receptor () | BDBM50049481 ((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...) | Reactome pathway KEGG GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro growth hormone release was determined in rat pituitary cell assay | Bioorg Med Chem Lett 8: 107-12 (1999) BindingDB Entry DOI: 10.7270/Q2XS5TJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Sus scrofa) | BDBM50049481 ((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk A/S Curated by ChEMBL | Assay Description Inhibition of the compound against pig growth hormone secretagogue (GHS) receptor | J Med Chem 47: 888-99 (2004) Article DOI: 10.1021/jm0309452 BindingDB Entry DOI: 10.7270/Q2SN08D0 | |||||||||||
More data for this Ligand-Target Pair |