BDBM50049767 2-[1-Thiophen-3-yl-meth-(E)-ylidene]-3,4-dihydro-2H-naphthalen-1-one::CHEMBL166974

SMILES: O=C1\C(CCc2ccccc12)=C\c1ccsc1

InChI Key: InChIKey=JCQSAWCIZPUUBS-UKTHLTGXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50049767 (2-[1-Thiophen-3-yl-meth-(E)-ylidene]-3,4-dihydro-2...) Show SMILES O=C1\C(CCc2ccccc12)=C\c1ccsc1 Show InChI InChI=1S/C15H12OS/c16-15-13(9-11-7-8-17-10-11)6-5-12-3-1-2-4-14(12)15/h1-4,7-10H,5-6H2/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universität de Saarlandes Curated by ChEMBL					Assay Description In vitro inhibitory activity against Cytochrome P450 19A1 using human placental microsomes.				J Med Chem 39: 834-41 (1996) Article DOI: 10.1021/jm950377t BindingDB Entry DOI: 10.7270/Q29K499J
					More data for this Ligand-Target Pair