BDBM50049782 2-[1-(2-Amino-thiazol-5-yl)-meth-(E)-ylidene]-3,4-dihydro-2H-naphthalen-1-one::CHEMBL355681

SMILES: Nc1ncc(\C=C2/CCc3ccccc3C2=O)s1

InChI Key: InChIKey=ZFYFUMAODCHFDN-JXMROGBWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50049782 (2-[1-(2-Amino-thiazol-5-yl)-meth-(E)-ylidene]-3,4-...) Show SMILES Nc1ncc(\C=C2/CCc3ccccc3C2=O)s1 Show InChI InChI=1S/C14H12N2OS/c15-14-16-8-11(18-14)7-10-6-5-9-3-1-2-4-12(9)13(10)17/h1-4,7-8H,5-6H2,(H2,15,16)/b10-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universität de Saarlandes Curated by ChEMBL					Assay Description In vitro inhibitory activity against Cytochrome P450 19A1 using human placental microsomes.				J Med Chem 39: 834-41 (1996) Article DOI: 10.1021/jm950377t BindingDB Entry DOI: 10.7270/Q29K499J
					More data for this Ligand-Target Pair