BDBM50049928 CHEMBL3317685

SMILES: CCOC(=O)c1cc2c3cccnc3cc(CCc3nc4ccccc4n3C)n2n1

InChI Key: InChIKey=KUGHRAHSLFOUTN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50049928 (CHEMBL3317685) Show SMILES CCOC(=O)c1cc2c3cccnc3cc(CCc3nc4ccccc4n3C)n2n1 Show InChI InChI=1S/C23H21N5O2/c1-3-30-23(29)19-14-21-16-7-6-12-24-18(16)13-15(28(21)26-19)10-11-22-25-17-8-4-5-9-20(17)27(22)2/h4-9,12-14H,3,10-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta counting				Eur J Med Chem 84: 181-93 (2014) Article DOI: 10.1016/j.ejmech.2014.07.020 BindingDB Entry DOI: 10.7270/Q2S1844K
					More data for this Ligand-Target Pair