BDBM50050502 CHEMBL3317851

SMILES: COc1ccc(OC)c(c1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1

InChI Key: InChIKey=YWXSEZVUTCEGSS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM50050502 (CHEMBL3317851) Show SMILES COc1ccc(OC)c(c1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1 Show InChI InChI=1S/C23H22N2O4/c1-15-6-4-7-16(12-15)22(26)24-17-8-5-9-18(13-17)25-23(27)20-14-19(28-2)10-11-21(20)29-3/h4-14H,1-3H3,(H,24,26)(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair
Potassium channel protein TASK-1 (Homo sapiens (Human))	BDBM50050502 (CHEMBL3317851) Show SMILES COc1ccc(OC)c(c1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1 Show InChI InChI=1S/C23H22N2O4/c1-15-6-4-7-16(12-15)22(26)24-17-8-5-9-18(13-17)25-23(27)20-14-19(28-2)10-11-21(20)29-3/h4-14H,1-3H3,(H,24,26)(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair