BindingDB logo
myBDB logout

BDBM50051243 2-Furan-2-yl-7-methyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine::CHEMBL277589

SMILES: Cn1ncc2c1nc(N)n1nc(nc21)-c1ccco1

InChI Key: InChIKey=DBOSLFUBDMMBMA-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051243   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50051243
PNG
(2-Furan-2-yl-7-methyl-7H-pyrazolo[4,3-e][1,2,4]tri...)
Show SMILES Cn1ncc2c1nc(N)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C11H9N7O/c1-17-9-6(5-13-17)10-14-8(7-3-2-4-19-7)16-18(10)11(12)15-9/h2-5H,1H3,(H2,12,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
101n/an/an/an/an/an/an/an/a



Università degli Studi di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal homogenates.


J Med Chem 39: 1164-71 (1996)


Article DOI: 10.1021/jm950746l
BindingDB Entry DOI: 10.7270/Q2NP23H4
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50051243
PNG
(2-Furan-2-yl-7-methyl-7H-pyrazolo[4,3-e][1,2,4]tri...)
Show SMILES Cn1ncc2c1nc(N)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C11H9N7O/c1-17-9-6(5-13-17)10-14-8(7-3-2-4-19-7)16-18(10)11(12)15-9/h2-5H,1H3,(H2,12,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
101n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding ability of adenosine A2a receptor by using [3H]-CGS- as radioligand in rat striatal homogenate


Bioorg Med Chem Lett 4: 2539-2544 (1994)


Article DOI: 10.1016/S0960-894X(01)80279-1
BindingDB Entry DOI: 10.7270/Q2Q81D1P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50051243
PNG
(2-Furan-2-yl-7-methyl-7H-pyrazolo[4,3-e][1,2,4]tri...)
Show SMILES Cn1ncc2c1nc(N)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C11H9N7O/c1-17-9-6(5-13-17)10-14-8(7-3-2-4-19-7)16-18(10)11(12)15-9/h2-5H,1H3,(H2,12,15)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
651n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding ability of adenosine A1 receptor by using [3H]-CHA as radioligand in rat whole brain homogenate


Bioorg Med Chem Lett 4: 2539-2544 (1994)


Article DOI: 10.1016/S0960-894X(01)80279-1
BindingDB Entry DOI: 10.7270/Q2Q81D1P
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50051243
PNG
(2-Furan-2-yl-7-methyl-7H-pyrazolo[4,3-e][1,2,4]tri...)
Show SMILES Cn1ncc2c1nc(N)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C11H9N7O/c1-17-9-6(5-13-17)10-14-8(7-3-2-4-19-7)16-18(10)11(12)15-9/h2-5H,1H3,(H2,12,15)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
651n/an/an/an/an/an/an/an/a



Università degli Studi di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CHA binding to Adenosine A1 receptor in rat whole brain homogenates.


J Med Chem 39: 1164-71 (1996)


Article DOI: 10.1021/jm950746l
BindingDB Entry DOI: 10.7270/Q2NP23H4
More data for this
Ligand-Target Pair