BDBM50051516 CHEMBL79213::[(2S,3aS,7aS)-2-(Pyrrolidine-1-carbonyl)-octahydro-indol-1-yl]-((1R,2S)-2-p-tolyl-cyclopropyl)-methanone

SMILES: Cc1ccc(cc1)[C@H]1C[C@H]1C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1

InChI Key: InChIKey=GGVZIOUZLAKIJT-MNVIUDHYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051516 (CHEMBL79213 | [(2S,3aS,7aS)-2-(Pyrrolidine-1-carbo...) Show SMILES Cc1ccc(cc1)[C@H]1C[C@H]1C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C24H32N2O2/c1-16-8-10-17(11-9-16)19-15-20(19)23(27)26-21-7-3-2-6-18(21)14-22(26)24(28)25-12-4-5-13-25/h8-11,18-22H,2-7,12-15H2,1H3/t18-,19+,20+,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair