BDBM50051951 CHEMBL544005::[2-(2-Fluoro-phenyl)-cyclopropyl]-dipropyl-amine; hydrochloride
SMILES: CCCN(CCC)C1CC1c1ccccc1F
InChI Key: InChIKey=IDIJMAQOOZIZRH-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50051951![]() (CHEMBL544005 | [2-(2-Fluoro-phenyl)-cyclopropyl]-d...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT as radioligand; range=48-77 | J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN | |||||||||||
More data for this Ligand-Target Pair |