BDBM50052643 CHEMBL3318568

SMILES: O=C(N1CCN(CC1)c1ncccn1)c1ccc(OCCc2ccccc2)cc1

InChI Key: InChIKey=HNGOEZIXQROMGA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052643   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent proline transporter (Homo sapiens (Human))	BDBM50052643 (CHEMBL3318568) Show SMILES O=C(N1CCN(CC1)c1ncccn1)c1ccc(OCCc2ccccc2)cc1 Show InChI InChI=1S/C23H24N4O2/c28-22(26-14-16-27(17-15-26)23-24-12-4-13-25-23)20-7-9-21(10-8-20)29-18-11-19-5-2-1-3-6-19/h1-10,12-13H,11,14-18H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human high-affinity L-proline transporter expressed in COS1 cells by [3H]proline uptake assay				Bioorg Med Chem Lett 24: 3886-90 (2014) Article DOI: 10.1016/j.bmcl.2014.06.049 BindingDB Entry DOI: 10.7270/Q20C4XDG
					More data for this Ligand-Target Pair