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SMILES: FC(F)(F)Oc1cccc(c1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1ncccn1

InChI Key: InChIKey=VEBHUNRIWMOSAA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052662   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent proline transporter


(Homo sapiens (Human))		BDBM50052662
PNG
(CHEMBL3318550)
Show SMILES FC(F)(F)Oc1cccc(c1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C22H19F3N4O2/c23-22(24,25)31-19-4-1-3-18(15-19)16-5-7-17(8-6-16)20(30)28-11-13-29(14-12-28)21-26-9-2-10-27-21/h1-10,15H,11-14H2
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Article
PubMed
n/an/a 73n/an/an/an/an/an/a



Lexicon Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of human high-affinity L-proline transporter expressed in COS1 cells by [3H]proline uptake assay

Bioorg Med Chem Lett 24: 3886-90 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.049
BindingDB Entry DOI: 10.7270/Q20C4XDG
More data for this
Ligand-Target Pair