BDBM50052862 1-((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl)-ethanone::CHEMBL324372

SMILES: COc1c(ccc2C[C@H]3N(C)CCc4cccc(c34)-c12)C(C)=O

InChI Key: InChIKey=RXDUVKIICDGRRM-QGZVFWFLSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50052862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50052862 (1-((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1c(ccc2C[C@H]3N(C)CCc4cccc(c34)-c12)C(C)=O Show InChI InChI=1S/C20H21NO2/c1-12(22)15-8-7-14-11-17-18-13(9-10-21(17)2)5-4-6-16(18)19(14)20(15)23-3/h4-8,17H,9-11H2,1-3H3/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.				J Med Chem 39: 3491-502 (1996) Article DOI: 10.1021/jm960188q BindingDB Entry DOI: 10.7270/Q2XW4HXS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50052862 (1-((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1c(ccc2C[C@H]3N(C)CCc4cccc(c34)-c12)C(C)=O Show InChI InChI=1S/C20H21NO2/c1-12(22)15-8-7-14-11-17-18-13(9-10-21(17)2)5-4-6-16(18)19(14)20(15)23-3/h4-8,17H,9-11H2,1-3H3/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro affinity at human cloned Dopamine receptor D2A by [3H]-raclopride displacement.				J Med Chem 39: 3491-502 (1996) Article DOI: 10.1021/jm960188q BindingDB Entry DOI: 10.7270/Q2XW4HXS
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50052862 (1-((R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1c(ccc2C[C@H]3N(C)CCc4cccc(c34)-c12)C(C)=O Show InChI InChI=1S/C20H21NO2/c1-12(22)15-8-7-14-11-17-18-13(9-10-21(17)2)5-4-6-16(18)19(14)20(15)23-3/h4-8,17H,9-11H2,1-3H3/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro affinity at Dopamine receptor D1 of rat striatum by [3H]-SCH-23,390 displacement.				J Med Chem 39: 3491-502 (1996) Article DOI: 10.1021/jm960188q BindingDB Entry DOI: 10.7270/Q2XW4HXS
					More data for this Ligand-Target Pair