BDBM50053106 CHEMBL120112::[1-Aminooxalyl-2-ethyl-3-(3-trifluoromethyl-benzyl)-indolizin-8-yloxy]-acetic acid

SMILES: CCc1c(Cc2cccc(c2)C(F)(F)F)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O

InChI Key: InChIKey=NJPROSWBIXBLCH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2 (Homo sapiens (Human))	BDBM50053106 (CHEMBL120112 | [1-Aminooxalyl-2-ethyl-3-(3-trifluo...) Show SMILES CCc1c(Cc2cccc(c2)C(F)(F)F)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O Show InChI InChI=1S/C22H19F3N2O5/c1-2-14-15(10-12-5-3-6-13(9-12)22(23,24)25)27-8-4-7-16(32-11-17(28)29)19(27)18(14)20(30)21(26)31/h3-9H,2,10-11H2,1H3,(H2,26,31)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.				J Med Chem 39: 3636-58 (1996) Article DOI: 10.1021/jm960395q BindingDB Entry DOI: 10.7270/Q2NC609M
					More data for this Ligand-Target Pair
Phospholipase A2 (Homo sapiens (Human))	BDBM50053106 (CHEMBL120112 | [1-Aminooxalyl-2-ethyl-3-(3-trifluo...) Show SMILES CCc1c(Cc2cccc(c2)C(F)(F)F)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O Show InChI InChI=1S/C22H19F3N2O5/c1-2-14-15(10-12-5-3-6-13(9-12)22(23,24)25)27-8-4-7-16(32-11-17(28)29)19(27)18(14)20(30)21(26)31/h3-9H,2,10-11H2,1H3,(H2,26,31)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).				J Med Chem 39: 3636-58 (1996) Article DOI: 10.1021/jm960395q BindingDB Entry DOI: 10.7270/Q2NC609M
					More data for this Ligand-Target Pair