BDBM50053518 4-{3-[5-Furan-3-yl-7-(3-methyl-1H-tetrazol-5-yl)-naphthalen-2-yloxymethyl]-phenyl}-tetrahydro-pyran-4-ol::CHEMBL338132

SMILES: Cn1nnc(n1)-c1cc(-c2ccoc2)c2ccc(OCc3cccc(c3)C3(O)CCOCC3)cc2c1

InChI Key: InChIKey=CKLYTSMWXULDEQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50053518 (4-{3-[5-Furan-3-yl-7-(3-methyl-1H-tetrazol-5-yl)-n...) Show SMILES Cn1nnc(n1)-c1cc(-c2ccoc2)c2ccc(OCc3cccc(c3)C3(O)CCOCC3)cc2c1 Show InChI InChI=1S/C28H26N4O4/c1-32-30-27(29-31-32)22-14-21-15-24(5-6-25(21)26(16-22)20-7-10-35-18-20)36-17-19-3-2-4-23(13-19)28(33)8-11-34-12-9-28/h2-7,10,13-16,18,33H,8-9,11-12,17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenase				J Med Chem 39: 3951-70 (1996) Article DOI: 10.1021/jm960301c BindingDB Entry DOI: 10.7270/Q2639QCJ
					More data for this Ligand-Target Pair