BDBM50053521 7-[3-(4-Hydroxy-tetrahydro-pyran-4-yl)-benzyloxy]-4-phenyl-naphthalene-2-carbonitrile::CHEMBL129916

SMILES: OC1(CCOCC1)c1cccc(COc2ccc3c(cc(cc3c2)C#N)-c2ccccc2)c1

InChI Key: InChIKey=AEZYXJBLXSOKID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50053521 (7-[3-(4-Hydroxy-tetrahydro-pyran-4-yl)-benzyloxy]-...) Show SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(cc(cc3c2)C#N)-c2ccccc2)c1 Show InChI InChI=1S/C29H25NO3/c30-19-22-15-24-18-26(9-10-27(24)28(17-22)23-6-2-1-3-7-23)33-20-21-5-4-8-25(16-21)29(31)11-13-32-14-12-29/h1-10,15-18,31H,11-14,20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenase				J Med Chem 39: 3951-70 (1996) Article DOI: 10.1021/jm960301c BindingDB Entry DOI: 10.7270/Q2639QCJ
					More data for this Ligand-Target Pair